The clinical research of modified chailing paste treated small volume prostatic hyperplasia with chronic prostatitis patients after TURP about LUTS and bladder neck contracture

Abstract

Objective: To explore the clinical effect and safety of modified Chailing paste on improving postoperative lower urinary tract symptoms (LUTS) and bladder neck contracture in pa-tients with small-volume prostatic hyperplasia (SBPH) complicated with chronic prostatitis after transurethral resection of the prostate (TURP).

Methods: A total of 145 patients with SBPH were enrolled in a randomized double-blind placebo-controlled study and randomly divided into three groups. Group A (49 patients) underwent simple TURP, Group B (48 patients) underwent TURP combined with postoperative Tamsulosin, and Group C (48 pa-tients) underwent TURP combined with modified Chailing paste. Tissue specimens from all patients were sent for pathological examination. Data were analyzed using SPSS22.0 statistical software.

Results: The study followed up 141 patients. The detection rate of his-tological prostatitis (HP) was 92.91%. Significant improvements in residual urine volume (PVR), International Prostate Symptom Score (IPSS), quality of life (QOL) score, and max-imum urine flow rate (Qmax) were observed in all groups before and 3 months after surgery (P < 0.01). Group C showed statistically significant improvement compared to Groups A and B (P < 0.05). The incidence of bladder neck contracture 12 months post-operation was significantly lower in Group C compared to Groups A and B (P < 0.05).

Conclusion: Modified Chailing paste significantly improves postoperative LUTS symptoms and qual-ity of life and reduces the incidence of bladder neck contracture in patients with SBPH complicated with chronic prostatitis after TURP.